S. Clay Isom

Animal, Dairy and Veterinary Sciences

Developmental Genetics & Epigenetics


S. Clay Isom

Contact Information

Office Location: AGRS 243
Phone: (435) 797-8114
Email: clay.isom@usu.edu

Educational Background

PhD, Animal Sciences, University of Missouri, 2006
BS, Animal Science, Utah State University, 2000

Biography

Born & raised in Lyman, Wyoming.

Teaching Interests

Reproductive physiology

Research Interests

epigenetics, embryo/environment interactions, preimplantation embryo development, oocyte quality

Awards

Teacher of the Year, 2016

ADVS Department

Teacher of the Year, 2016

CAAS

Teacher of the Year, 2015

ADVS Department

Graduate Research Mentor of the Year, 2014

ADVS

Graduate Research Mentor of the Year, 2014

CAAS

Dorris D. & Christine M. Brown Graduate Research Fellowship, 2003

University of Missouri–Columbia

USDA National Needs Travel Award, 2003

University of Missouri–Columbia

USDA/CSREES National Needs Graduate Student Fellowship, 2000

University of Missouri–Columbia

University Club Scholarship, 1997

Utah State University

University Club Scholarship, 1993

Utah State University


Publications | Abstracts

    An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

    Publications | Fact Sheets

      An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

      Publications | Journal Articles

      Academic Journal

      • Li, Q., Suasnavas, E., Heywood, S., Xiao, L., Zhou, A., Isom, S., (2015). Biochemical, biophysical and genetic changes of porcine trophoblast-derived stem-like cells during differentiation as evaluated using Raman microspectroscopy, Atomic force microscopy and quantitative polymerase chain reaction. genesis , The Journal of Genetics and Development , 53:12, 749-761. doi: doi: 10.1002/dvg.22907
      • Li, Q., Suasnavas, E., Xiao, L., Heywood, S., Qi, X., Zhou, A., Isom, S., (2015). Label-Free and Non-Invasive Monitoring of Porcine Trophoblast Derived Cells: Differentiation in Serum and Serum-Free Media. Journal of Biophotonics, 8:8, 638-645. doi: doi:10.1002/jbio.201400062
      • Cox, L., Vanderwall, D.K, Parkinson, K.C, Sweat, L., Isom, S., (2015). Expression profiles of select genes in cumulus-oocyte complexes from young and aged mares. Reproduction Fertility & Development, doi: doi: 10.1071/RD14446
      • Sanz-Fernandez, M., Johnson, J., Abuajamieh, M., Stoakes, S., Seibert, J., Cox, L., Kahl, S., Elsasser, T., Ross, J., Isom, S., Rhoads, R., Baumgard, L., (2015). . Effects of heat stress on carbohydrate and lipid metabolism in growing pigs. Physiol Rep, 3:2, doi: doi: 10.14814/phy2.12315
      • Suasnavas, E., Heywood, S., Ward, A., Cox, L., O'Grady, M., Zhao, Y., Isom, S., (2015). Isolation and characterization of trophoblast-derived stem-like cells from peri-implantation porcine embryos. Animal Reproduction Science, 154, 128-141. doi: doi: 10.1016/j.anireprosci.2015.01.012
      • Saunders, G., Stevens, J.R, Isom, S., (2014). A shortcut for multiple testing on the directed acyclic graph of Gene Ontology. BMC Bioinformatics, 15:349, doi: DOI: 10.1186/s12859-014-0349-3
      • Suasnavas, E., Heywood, S., Ward, A., Cox, L., O'Grady, M., Zhao, Y., Isom, S., Characterization of trophoblast-derived stem-like cells from peri-implantation porcine embryos.. Animal Reproduction Science
      • Isom, S., Stevens, J.R, Li, R., Spollen, W., Cox, L., Spate, L., Murphy, C., Prather, R., (2013). Transcriptional profiling by RNA-Seq of peri-attachment porcine embryos generated using a variety of assisted reproductive technologies (ART). Physiol Genomics, 45:14, 577-589. doi: 10.1152/physiolgenomics.00094.2012
      • Morrill, B.H, Cox, L., Ward, A., Heywood, S., Isom, S., Targeted DNA methylation analysis by high throughput sequencing in porcine peri-attachment embryos. Journal of Reproduction and Development
      • Isom, S., Li, R., Whitworth, K.M, Prather, R.S, Timing of First Embryonic Cleavage Is a Positive Indicator of the In Vitro Developmental Potential of Porcine Embryos Derived From In Vitro Fertilization, Somatic Cell Nuclear Transfer and Parthenogenesis. Molecular Reproduction and Development, doi: 10.1002/mrd.22013
      • Zhao, M., Whitworth, K., Lin, H., Zhang, X., Isom, S., Dobbs, K., Bauer, B., Prather, R., (2010). Porcine skin-derived progenitor (SKP) spheres and neurospheres: Distinct "stemness" identified by microarray analysis. Cell Reprogram, 12:3, 329-345.
      • Isom, S., Prather, R., Rucker, E., (2009). Enhanced developmental potential of heat shocked porcine parthenogenetic embryos is related to accelerated mitogen-activated protein kinase dephosphorylation. Society of Reproductive and Fertility Supplement, 21:7, 892-900.
      • Prather, R., Ross, J., Isom, S., Green, J., (2009). Transcriptional, post-transcriptional and epigenetic control of porcine oocyte maturation and embryogenesis. Society of Reproductive and Fertility Supplement, 66, 165-176.
      • Isom, S., Lai, L., Prather, R., Rucker, E., (2009). Response of porcine cleavage-stage embryos to heat shock depends on timing of stressor application relative to oocyte activation. Molecular Reproduction & Development, 76:6, 548-554.
      • Zhao, M., Isom, S., Lin, H., Hao, Y., Zhao, J., Whyte, J., Doggs, K., Zhang, Y., Prather, R., (2009). Tracing the stemness of porcine skin derived progenitors (pSKP) back to specific marker gene expression. Cloning Stem Cells, 11:1, 111-122.
      • Li, R., Whitworth, K., Lai, L., Wax, D., Spate, L., Murphy, C., Rieke, A., Isom, S., Hao, Y., Zhong, Z., Katayama, M., Schatten, H., Prather, R., (2007). Concentration and composition of free amino acids and osmolalities of porcine oviductal and uterine fluid and their effects on development of porcine embryos. Molecular Reproduction & Development, 74, 1228-1235.
      • Isom, S., Prather, P., Rucker III, E., (2007). Heat stress-induced apoptosis in porcine in vitro fertilized and parthenogenetic preimplantation-stage embryos. Molecular Reproduction & Development, 74, 574-581.
      • Li, R., Murphy, C., Spate, L., Wax, D., Isom, S., Rieke, A., Walters, E., Samuel, M., Prather, R., (2007). Production of piglets after cryopreservation of embryos using a centrifugation-based method for delipation without micromanipulation. Molecular Reproduction & Development, 74, 1228-1235.

      An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

      Publications | MultiMedia

      An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

      Publications | Other

      Other

        An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

        Teaching

        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2020
        ADVS 4920 - Undergraduate Seminar, Fall 2020
        ADVS 6800 - Graduate Student Seminar, Spring 2020
        ADVS 4920 - Undergraduate Seminar, Spring 2020
        ADVS 6700 - Epigenetics, Fall 2019
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2019
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2019
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2019
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2019
        ADVS 4920 - Undergraduate Seminar, Fall 2019
        ADVS 6800 - Graduate Student Seminar, Spring 2019
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2018
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2018
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2018
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2018
        ADVS 6800 - Graduate Student Seminar, Spring 2018
        ADVS 6700 - Epigenetics, Fall 2017
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2017
        ADVS 6800 - Graduate Student Seminar, Spring 2017
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2016
        ADVS 6800 - Graduate Student Seminar, Spring 2016
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2015
        ADVS 6900 - Special Problems, Fall 2015
        ADVS 6800 - Graduate Student Seminar, Spring 2015
        ADVS 6200 - Physiology of Reproduction, Fall 2014
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2014
        ADVS 6800 - Graduate Student Seminar, Spring 2014
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2013
        ADVS 6200 - Physiology of Reproduction, Fall 2012
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2012
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2012
        ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2012
        ADVS 4200 - Physiology of Reproduction and Lactation, Spring 2012
        ADVS 4200 - LABORATORY, Spring 2011
        ADVS 4200 - LABORATORY, Spring 2011
        ADVS 4200 - PHYL OF REPROD/LACTN (CI), Spring 2011
        ADVS 4200 - Physiology of Reprodution and Lactation, Spring 2011
        AG 422 - Physiology of Reproduction, 2007

        Graduate Students Mentored

        Edison Suasnavas, Animal, Dairy and Veterinary Sciences, September 2010
        Laura Moley, Animal, Dairy and Veterinary Sciences 2019
        Sameer Alhojaily, Animal, Dairy and Veterinary Sciences 2019
        Yuanfeng Zhao, Animal, Dairy and Veterinary Sciences 2019
        Lindsay Cox, Animal, Dairy and Veterinary Sciences, September 2011 - August 2016