Irina Polejaeva
Animal, Dairy & Veterinary Sciences (ADVS)
Developmental Biology

Educational Background
Expertise
Large Animal Transgenic Models, Animal Cloning // Program goals: Production of transgenic animals using somatic cell nuclear transfer technology (SCNT or cloning) for biomedical and agricultural applications
Biography
Dr. Polejaeva is currently a Professor. She joined the ADVS department in April 2011 as an Associate Professor. She is a member of the Veterinary Diagnostics and Infectious Disease USTAR team and Utah Collaborative Arrhythmia Program.
Research Interests
The area of her research interest includes:
• Production of transgenic animals using somatic cell nuclear transfer technology (cloning) for biomedical and agricultural applications;
• Improve efficiency of Somatic Cell Nuclear Transfer (SCNT) through understanding molecular mechanism of epigenetic reprogramming;
• Development of accurate pre-implantation embryo assessment methods using combination of individual embryo culture system, imaging and gene expression/metabolomic analysis
Awards
Outstanding graduate mentor of the year, 2023
USU
The CAAS Faculty Researcher of the Year , 2020
CAAS
The ADVS Faculty Researcher of the Year , 2020
ADVS, USU
The ADVS Department Graduate Research Mentor of the Year Award, 2018
ADVS, USU
Best of Basic Science, 2013
American Heart Association Scientific Sessions
Publications | Abstracts
- Perisse, I.V, Fan, Z., Liu, Y., Vaghela, N., Patrick, T., Regouski, M., Van Wettere, A., Leir, S., Harris, A., White, K.L, Polejaeva, I., (2024). Towards Genetic Correction of Meconium Ileus by Intestinal Expression of CFTR in CFTR-null Sheep Model. Cystic Fibrosis Foundation 2024 Research Conference
- Bennett, K., Beal, D., Liu, Y., Patrick, T., Bunderson, I., Moawad, A., Polejaeva, I., (2024). Effects of oxygen level on bovine oocyte maturation and embryo development. Reproduction, Fertility and Development
- Bunderson, I., Liu, Y., Polejaeva, I., (2024). Effects of serum-free maturation medium and resveratrol supplementation on ovine oocyte maturation and quality. Reproduction, Fertility and Development
- Adams, L., Liu, Y., Patrick, T., Grow, E., E. Ruggeri , E., B. Durrant, B., Polejaeva, I., (2024). Development of interspecies somatic cell nuclear transfer (iSCNT) caprine-bovine embryos injected with demethylase mRNA and mitochondrial extract. Reproduction, Fertility and Development
- Blocher, R., Liu, Y., Polejaeva, I., (2024). Nuclear assessment of bovine oocytes matured in cytokine-supplemented medium using microtubule and DNA staining. Reproduction, Fertility and Development
- Regouski, M., Liu, Y., Rutigliano, H., Polejaeva, I., (2023). MP-453085-7 PROGESTERONE WITHDRAWAL ASSOCIATED WITH INCREASED ATRIAL FIBRILLATION SUSCEPTIBILITY IN FEMALES. Heart Rhythm
- Adams, L., Liu, Y., B. Durrant, B., Young, C., E. Ruggeri , E., R. Krisher, R., Patrick, T., Polejaeva, I., (2023). Quantification of mitochondrial DNA copy number in interspecies somatic cell nuclear transfer embryos. Reproduction, Fertility and Development
- Blocher, R., Liu, Y., Adams, L., Polejaeva, I., (2023). Evaluation of mitochondrial quantity and distribution in bovine oocytes matured in cytokine-supplemented medium. Reproduction, Fertility and Development
- Kuczynski,, C., Perisse, ., Regouski, M., Alipour, E., LaPradd, C., Liu, Y., Beaty, M., Kim-Shapiro, D., Atala, A., Polejaeva, I., Porada, C., Almeida-Porada, M., (2022). Novel Sheep Model of Sickle Cell Disease Reproduces Human Clinical and Laboratory Parameters. Blood
- Su, Y., Wang, L., Fan, Z., Liu, Y., Zhu, J., Kaback, D., Oudiz, J., Patrick, T., Yee, S., Tian, X., Polejaeva, I., Tang, Y., (2021). Establishment of bovine induced pluripotent stem cells. Reproduction, fertility, and development
- Adams, L., Liu, Y., Durrant, B., Ruggeri, E., Young, C., Polejaeva, I., (2021). Use of a hand-made cloning protocol to reduce oocyte mitochondria. Reproduction, Fertility and Development
- Keim, J., Liu, Y., Regousk, M., Stott, R.D, Singina, G.N, Polejaeva, I., (2021). Effect of cytokine-supplemented maturation medium on bovine somatic cell nuclear transfer embryo development. Reproduction, Fertility and Development
- Keim, J., Zhang, W., Liu, Y., Rutigliano, H., Zhou, A., Polejaeva, I., (2020). Analyzing metabolomic profile of bovine IVF and somatic cell nuclear transfer embryos through Raman spectroscopy. Reproduction, Fertility and Development
- Fan, Z., Regouski, M., Liu, Y., Keim, J., Perisse, I., Oatley, J., Polejaeva, I., (2020). Generation of NANOS2 knockout goats using CRISPR/Cas9 and somatic cell nuclear transfer techniques. Reproduction, Fertility and Development
- Keim, J., Zhang, W., Rutigliano, H., Zhou, A., Polejaeva, I., (2020). Analyzing metabolomic profile of bovine IVF and SCNT embryos through Raman spectroscopy. Reproduction, Fertility and Development
- Keim, J., Liu, Y., Polejaeva, I., (2019). Increasing in vitro embryonic development through improved oocyte maturation in cattle oocytes. Reproduction, Fertility and Development
- Perisse, I.V, Fan, Z., Liu, Y., Regouski, M., Van Wettere, A., Wang, Z., Harris, A., White, K.L, Polejaeva, I., (2019). Towards the correction of meconium ileus with cystic fibrosis transmembrane conductance regulator (CFTR) intestinal expression in CFTR knockout sheep. Reproduction, Fertility and Development
- Thomas, A., Jones, R., Regouski, M., Polejaeva, I., Davies, C., (2016). Identification of Transgene Insertion Sites by Target Selection and Next-Generation Sequencing. Proceedings of the Large Animal Genetics Engineering Summit
- Polejaeva, I., Ranjan, R., Davies, C., White, K.L, (2016). TGF-β1 Transgenic Goat Model of Atrial Fibrillation. Proceedings of the Large Animal Genetics Engineering Summit
- Hu, S., Hall, J., Wang, Z., Polejaeva, I., (2014). TALEN-mediated targeted insertion of transforming growth factor-β1 (TGF-β1) gene into the goat AAVS1 locus. . Transgenic research
- Polejaeva, I., Ranjan, R., Wang, Z., Olsen, A.L, Davies, C., White, K.L, (2014). Transgenic goat models to study cardiac fibrosis and atrial fibrillation. Transgenic research
- Hall, J., Yang, M., Meng, Q., Dai, J., Polejaeva, I., (2014). Effect of follicular size of cytoplast donor on cloning efficiency in goats.. Reproduction, Fertility and Development
- Hu, S., Wang, Z., Polejaeva, I., (2014). Knockout of goat nucleoporin 155 (NUP155) gene using CRISPR/CAS9 systems.. Reproduction, Fertility and Development
- Polejaeva, I., Ranjan, R., Hall, J., Rutigliano, H., Thomas, A.J, Dosdall, D., MacLeod, R., Marrouche, N., Wang, Z., Olsen, A.L, White, K.L, Davies, C., (2013). Cardiac specific overexpression of Transforming Growth Factor Beta1 (TGF-Beta1) increases susceptibility to atrial fibrillation in transgenic goats. Circulation
- Rutigliano, H., Wilhelm, A., Hall, J., Sessions, B., Meng, Q., White, K.L, Bunch, T.D, Davies, C., Polejaeva, I., (2013). Aberrant gene expression at the fetal-maternal interface in sheep and goats produced by somatic cell nuclear transfer. Amernican Journal of Reproductive Immunology
- Hall, J., Meng, Q., Sessions, B.R, Fan, Z., Wang, X., Stott, R.D, Rutigliano, H., Davies, C., Panter, K., Bunch, T.D, White, K.L, Polejaeva, I., (2012). Effect of embryo culture length on production of cloned transgenic goats. Reproduction, Fertility & Develpment
- Meng, Q., Hall, J., Rutigliano, H., Zhou, X., Sessions, B.R, Stott, R.D, Panter, K., Davies, C., Ranjan, R., Dosdall, D., MacLeod, R., Marrouche, N., White, K.L, Wang, Z., Polejaeva, I., (2012). Generation of cloned transgenic goats with cardiac specific overexpression of transforming growth factor β1. Reproduction, Fertility & Develpment
- Polejaeva, I., Hall, J., Meng, Q., Zhou, X., Sessions, B.R, Panter, K., Stott, R.D, Rutigliano, H.M, Davies, C., Wang, Z., Ranjan, R., Dosdall, D., MacLeod, R., Marouche, N., White, K.L, (2012). Development of a transgenic goat model with cardiac-specific overexpression of human transforming growth factor-β1 to study the relationship between atrial fibrosis and atrial fibrillation. Circulation Research
- Tessanne, K., Stroud, T., Long, C., Sadeghieh, S., Hwang, E., Chen, S., Polejaeva, I., Westhusin, M., (2009). Development of transgenic livestock with reduced myostatin expression using RNA interference. Reproduction, Fertility and Development
- Xiang, T., Walker, S., Gregg, K., Zhou, W., Farrar, V., Sadeghieh, S., Hwang, W., Findeisen, B., Arenivas, F., Polejaeva, I., (2009). Reprogramming of Oct-4 following equine somatic cell nuclear transfer. Reproduction, Fertility and Development
- Gregg, K., Chen, S., Sadeghieh, S., Guerra, T., Xiang, T., Meredith, J., Polejaeva, I., (2009). Risk assessment of infectious disease transmission via in vitro embryo production using somatic cell nucleus transfer. Reproduction, Fertility and Development
- Ayaers, D., Kind, A., Schnieke, A., Campbell, K., McCreath, K., Howcroft, J., Emslie, L., Mycock, K., Gibson, Y., Dai, Y., Polejaeva, I., Phelps, C., Geyer, C., Vaught, T., Mullins, J., Coleman, A., (1999). Gene targeting in livestock. Transgenic research
- Polejaeva, I., Ashktorab, H., Bunch, T., Ellis, L., Reed, W., White, K., (1996). Stable transfection of mink embryonic stem (ES) cells and the expression of green fluorescent protein under cytomegalovirus promoter control. Theriogenology
- White, K., Polejaeva, I., Bunch, T., Suh, T., Reed, W., Spendlove, R., Wilkinson, R., (1995). Effect of non-serum supplemented media on establishment and maintenance of bovine embryonic stem-like cells. Theriogenology
- Polejaeva, I., White, K., Ellis, L., Reed, W., (1995). Isolation and long-term culture of mink and bovine embryonic stem-like cells. Theriogenology
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.
- Polejaeva, I., (2006). A double nuclear transfer technique for cloning pigs. : Methods of Molecular Biology. Methods of Molecular Biology.
Publications | Book Chapters
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.
Publications | Journal Articles
Academic Journal
- Song, B., Frank, J.C, Yun, S., Julander, J.G, Mason, J.B, Polejaeva, I.A, Davies, C.J, White, K.L, Dai, X., Lee, Y., (2024). Comparison of three chimeric Zika vaccine prototypes developed on the genetic background of the clinically proven live-attenuated Japanese encephalitis vaccine SA14-14-2. International Journal of Molecular Sciences (Int J Mol Sci), 26:1, 195.
- Kwan, E., Ghafoori, E., Good, W., Regouski, M., Moon, B., Fish, J., Hsu, E., Polejaeva, I.A, MacLeod, R.S, Dosdall, D.J, Ranjan, R., (2024). Diffuse functional and structural abnormalities in fibrosis: Potential structural basis for sustaining atrial fibrillation. Heart Rhythm, doi: https://doi.org/10.1016/j.hrthm.2024.10.060
- Adams, L., Liu, Y., Polejaeva, I., (2024). Current status of interspecies somatic cell nuclear transfer and meta‐analysis of the effects of phylogenetic distance on embryonic and fetal development. Mammal Review, 54, 387-403.
- Gibson, S.A, Liu, Y., Li, R., Hurst, B., Fan, Z., Siddharthan, V., Larson, D.P, Sheesley, A.Y, Stewart, R., Kunzler, M., Polejaeva, I., Van Wettere, A., Moisyadi, S., Morrey, J.D, Tarbet, B., Wang, Z., (2024). Differences in Susceptibility to SARS-CoV-2 Infection Among Transgenic hACE2-Hamster Founder Lines. Viruses, 16:10, doi: 10.3390/v16101625
- Leir, S., Tkachenko, S., Paranjapye, ., Meckler, F., Van Wettere, A., Kerschner, J.L, Kuznetsov, E., Schacht, M., Gillurkar, ., Regouski, M., Perisse, I.V, Marriott, C.M, Liu, Y., Bunderson, I., White, K.L, Polejaeva, I., Harris, A., (2024). Stellate cells are in utero markers of pancreatic disease in cystic fibrosis.. Molecular Medicine, 30, 115.
- Blocher, R., Liu, Y., Patrick, T., Polejaeva, I., (2024). Cytokine-Supplemented Maturation Medium Enhances Cytoplasmic and Nuclear Maturation in Bovine Oocytes. Animals , 14, 1837.
- Liu, Y., Stott, R.D, Regouski, M., Fan, Z., Perisse, I.V, Patrick, T., Keim, J., Meng, Q., Polejaeva, I., (2024). A retrospective analysis of sheep generated by somatic cell nuclear transfer.. Theriogenology, 227, 102-111. doi: 10.1016/j.theriogenology.2024.07.017
- Keim, J., Liu, Y., Regouski, M., Stott, R.D, Singina, G.N, White, K.L, Polejaeva, I., (2023). Cytokine supplemented maturation medium improved development to term following somatic cell nuclear transfer (SCNT) in cattle. Reproduction, Fertility and Development, 35, 575-588.
- Van Wettere, A., Leir, S.H, Cotton, C.U, Regouski, M., Perisse, I.V, Kerschner, J.L, Paranjapye, A., Fan, Z., Liu, Y., Schacht, M., White, K.L, Polejaeva, I., Harris, A., (2023). Early developmental phenotypes in the cystic fibrosis sheep model.. FASEB bioAdvances, 5:1, 13-26.
- Davies, C.J, Fan, Z., Morgado, .P, Liu, Y., Regouski, M., Meng, Q., Thomas, A.J, Yun, S., Byung-Hak, B., Frank, J.C, Perisse, I.V, Van Wettere, A., Lee, Y., Polejaeva, I., (2022). Development and characterization of type I interferon receptor knockout sheep: A model for viral immunology and reproductive signaling. Frontiers in Genetics, 13, 986316. doi: 10.3389/fgene.2022.986316
- Perisse, I.V, Fan, Z., Singina, G.N, White, K.L, Polejaeva, I., (2021). Improvements in Gene Editing Technology Boost Its Applications in Livestock. Frontiers in Genetics, 11, doi: 10.3389/fgene.2020.614688
- Su, Y., Wang, L., Fan, Z., Liu, Y., Zhu, J., Kaback, D., Oudiz, J., Patrick, T., Yee, S.P, Tian, X.C, Polejaeva, I., Tang, Y., (2021). Establishment of Bovine-Induced Pluripotent Stem Cells. International journal of molecular sciences, 22:19, 10489.
- Perisse, I.V, Fan, Z., Van Wettere, A., Liu, Y., Leir, S., Keim, J., Regouski, M., Wilson, M.D, Cholewa, K.M, Mansbach, S.N, Kelley, T.J, Wang, Z., Harris, A., White, K.L, Polejaeva, I., (2021). Sheep models of F508del and G542X cystic fibrosis mutations show cellular responses to human therapeutics. FASEB BioAdvances, 3:10, 841.
- Cuthbert, J.M, Russell, S.J, Polejaeva, I., Meng, Q., White, K.L, Benninghoff, A., (2021). Comparing mRNA and sncRNA profiles during the maternal-to-embryonic transition in bovine IVF and scNT embryos.. Biology of Reproduction, 105:6, 1401–1415. doi: 10.1093/biolre/ioab169
- Cuthbert, J.M, Russell, S.J, Polejaeva, I.A, Meng, Q., White, K.L, Benninghoff, A.D, (2021). Dynamics of small non-coding RNAs in bovine scNT embryos through the maternal-to-embryonic transition. Biology of Reproduction, 105:4, 918-933. doi: 10.1093/biolre/ioab107
- Ciccarelli, M., Giassetti, M.I, Miao, D., Oatley, M.J, Robbins, C., Lopez-Biladeau, B., Waqas, M.S, Tibary, A., Whitelaw, B., Lillico, S., Park, C., Park, K., Telugu, B., Fan, Z., Liu, Y., Regouski, M., Polejaeva, I., Oatley, J.M, (2020). Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males. Proceedings of the National Academy of Sciences, 117:39, 24195--24204.
- Fan, Z., Perisse, I.V, Cotton, C.U, Regouski, M., Meng, Q., Domb, C., Van Wettere, A., Wang, Z., Harris, A., White, K.L, Polejaeva, I., (2018). A sheep model of cystic fibrosis generated by CRISPR/Cas9 disruption of the CFTR gene. JCI Insight, 3:19, doi: 10.1172/jci.insight.123529
- Yun, S., Song, B., Frank, J.C, Julander, J.G, Olsen, A.L, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2018). Functional genomics and immunologic tools: the impact of viral and host genetic variations on the outcome of Zika virus infection. Viruses, 10:8, E422. doi: 10.3390/v10080422
- Rutigliano, H., Wilhelm, A., Hall, J., Shi, B., Meng, Q., Stott, R.D, Bunch, T.D, White, K.L, Davies, C., Polejaeva, I., (2017). Cytokine gene expression at the maternal-fetal interface after somatic cell nuclear transfer pregnancies in small ruminants.. Reproduction, Fertility, and Development, 29:4, 646-657. doi: doi:10.1071/RD15103
- Yang, M., Hall, j., Fan, Z., Regouski, M., Meng, Q., Rutigliano, H., Stott, R.D, Rood, K., Panter, K., Polejaeva, I., (2016). Oocytes from small and large follicles exhibit similar development competence following goat cloning despite their differences in meiotic and cytoplasmic maturation. Theriogenology, 86:9, 2302-2311.
- Polejaeva, I., Ranjan, R., Davies, C., Regouski, M., Hall, J., Olsen, A.L, Meng, Q., Rutigliano, H., Dosdall, D., Angel, N., Sachse, F., Seidel, T., Thomas, A., Stott, R.D, Panter, K., Lee, P., Van Wettere, A., Stevens, J.R, Wang, Z., MacLeod, R., Marrouche, N., White, K.L, (2016). Increased Susceptibility to Atrial Fibrillation Secondary to Atrial Fibrosis in Transgenic Goats Expressing Transforming Growth Factor-β1. Journal of Cardiovascular Electrophysiology. , 27:10, 1220-1229.
- Yun, S., Song, B., Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Comparison of the live-attenuated Japanese encephalitis vaccine SA14-14-2 strain with its pre-attenuated virulent parent SA14 strain: similarities and differences in vitro and in vivo. Journal of General Virology (J Gen Virol), 97:10, 2575-2591. doi: 10.1099/jgv.0.000574
- Yun, S., Song, B., Frank, J.C, Julander, J.G, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announcements (Genome Announc), 4:4, e00800-16. doi: 10.1128/genomeA.00800-16
- Yun, S., Song, B., Frank, J.C, Julander, J.G, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announcements (Genome Announc), 4:4, e00800-16. doi: 10.1128/genomeA.00800-16
- Martins, L.T, Polejaeva, I., N., (2016). Developmental outcome and related abnormalities in goats: comparison between somatic cell nuclear transfer- and in vivo-derived concepti during pregnancy through term.. Cellular reprogramming, 18:4, 264-279. doi: 10.1089/cell.2015.0082
- Polejaeva, I., Rutigliano, H., Wells, K.D, (2016). Livestock in biomedical research: history, current status and future prospective. Reproduction, Fertility and Development, 28:2, 112-124.
- Ni, W., Qiao, J., Hu, S., Zhao, X., Regouski, M., Yang, M., Polejaeva, I., Chen, C., (2014). Efficient gene knockout in goats using CRISPR/Cas9 system.. PLoS One, 2014, 9 (9), :e106718
- Gong, J., Chen, G., Wang, Z., Polejaeva, I., Silisga, R., Chen, C., Kao, C., Chen, L., (2014). Activation of human K-ras G12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells. . PLoS One, 9(3): e90059
- Zhou, W., Gosch, ., Guerra, T., Broek, D., Wu, G., Walker, S., Polejaeva, I., (2014). Amino acid profiles in first trimester amniotic fluids of healthy cloned pregnancies are similar to those of IVF pregnancies, but not nonviable cloned pregnancies . Theriogenology, 81:2, 225-229. doi: http://dx.doi.org/10.1016/j.theriogenology.2013.09.012
- Polejaeva, I., Broek, D., Walker, S., Zhou, W., Walton, M., Benninghoff, A., Faber, D., (2013). Longitudinal study of reproductive performance of female cattle produced by somatic cell nuclear transfer. PLoS One, 8:12, e84283. doi: 10.1371/journal.pone.0084283
- Polejaeva, I., Mitalipov, S., (2013). Stem cell potency and the ability to contribute to chimeric organisms. Reproduction , 145:3, R81-88. doi: 10.1530/REP-12-0396
- Mendicino, M., Ramsoondar, J., Phelps, C., Vaught, T., Ball, S., LeRoith, T., Monahan, J., Chen, S., Dandro, A., Boone, J., Jobst, P., Vance, A., Wertz, N., Bergman, Z., Sun, X., Polejaeva, I., Butlet, J., Dai, Y., Ayares, D., Wells, K., (2011). Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus. Transgenic Research, 20:3, 625-641.
- Gregg, K., Xiang, T., Arenivas, S., Hwang, E., Arenivas, F., Chen, S., Walker, S., Picou, A., Polejaeva, I., (2011). Risk assessment of porcine reproductive and Respiratory syndrome virus (PRRSV) transmission via somatic cell nuclear transfer (SCNT) embryo production using oocytes from commercial abattoirs. . Anim Reprod Sci, 125:1-4, 148-157.
- Ramsoondar, J., Mendicino, M., Phelps, C., Vaught, T., Ball, S., Monahan, J., Chen, S., Dandro, A., Boone, J., Jobst, P., Vance, A., Wertz, N., Polejaeva, I., Butler, J., Dai, Y., Ayares, D., Wells, K., (2011). Targeted disruption of the porcine immunoglobulin kappa light chain locus. Transgenic Research, 20:3, 643-653.
- Gregg, K., Gosch, G., Guerra, T., Chen, S., Xiang, T., Broek, D., Bruner, B., Polejaeva, I., (2010). Large scale in vivo risk assessment of bovine viral diarrhea virus (BVDV) transmission through transfer of bovine embryos produced via somatic cell nuclear transfer (SCNT).. Theriogenology, 74:7, 1264-70.
- Gregg, K., Riddell, K., Chen, S., Galik, P., Xiang, T., Guerra, T., Marley, M., Polejaeva, I., Givens, M., (2010). Risk and prevention of bovine viral diarrhea virus (BVDV) transmission through embryo production via somatic cell nuclear transfer (SCNT) using oocytes from persistently infected donors. . Theriogenology, 74:1, 1-10.
- Gregg, K., Chen, S., Guerra, T., Sadeghieh, S., Xing, T., Meredith, J., Polejaeva, I., (2009). A sensitive and efficient detection method for bovine viral diarrhea virus (BVDV) in single preimplantation bovine embryos.. Theriogenology, 71, 966-974.
- Gregg, K., Chen, S., Sadeghieh, S., Guerra, T., Xiang, T., Meredith, J., Polejaeva, I., (2009). Experimental risk assessment of bovine viral diarrhea virus transmission via in vitro embryo production using somatic cell nucleus transfer.. Theriogenology, 72:1, 99-110.
- Gregg, K., Polejaeva, I., (2009). Risk of equine infectious anemia virus disease transmission through in vitro embryo production using somatic cell nucleus transfer. Theriogenology, 72:3, 289-299.
- Zhou, W., Sadeghieh, S., Abruzzese, R., Uppada, S., Meredith, J., Ohlrichs, C., Broek, D., Polejaeva, I., (2009). Transcript levels of several epigenome regulatory genes in bovine somatic donor cells are not correlated with their cloning efficiency. . Cloning and Stem Cells, 11, 397-405.
- Zhou, W., Xiang, T., Walker, S., Abruzzese, R., Hwang, E., Farrar, V., Findeisen, B., Sadeghieh, S., Arenivas, F., Chen, S., Polejaeva, I., (2008). Aggregation of Bovine Cloned Embryos at the Four –Cell Stage Stimulated Gene Expression and In Vitro Embryo Development. Molecular Reproduction and Development, 75, 1281-1289.
- Zhou, W., Xiang, T., Walker, S., Farrar, V., Hwang, E., Findeisen, B., Sadeghieh, S., Arenivas, F., Abruzzese, R., Polejaeva, I., (2008). Global Gene Expression Analysis of Bovine Blastocysts Produced by Multiple Methods. Molecular Reproduction and Development, 75, 744-758.
- Walker, S., Christenson, R., Ruiz, R., Reeves, D., Pratt, S., Arenivas, F., Williams, N., Bruner, B., Polejaeva, I., (2007). Comparison of meat composition from offspring of cloned and conventionally produced boars. Theriogenology, 67, 178-184.
- Williams, N., Walker, S., Reeves, D., Sherrer, E., Galvin, J., Polejaeva, I., Rampacek, G., Benshek, L., Christenson, R., Graves, W., Pratt, S., (2006). A Comparison of Reproductive Characteristics of Boars Generated by Somatic Cell Nuclear Transfer to Highly Related Conventionally Produced Boars. Cloning and Stem Cells, 8, 130-139.
- Ji, W., Zhou, W., Abruzzese, R., Guo, W., Blake, A., Davis, S., Davis, S., Polejaeva, I., (2005). A method of determining zygosity of transgenic zebra fish by TaqMan real-time PCR. Analytical Biochem, 344:2, 240-246.
- Zhou, W., Abruzzese, R., Polejaeva, I., Davis, S., Davis, S., Ji, W., (2005). Amplification of nanogram amount of total RNA by the SMART-based PCR method for high-density oligonucleotide microarrays.. Clinical Chemistry, 51:12, 2354-2356.
- Gwazdauskas, F., Walters, A., McGilliard, M., Ball, S., Ellefson, N., Flesher, S., Keyes, L., Nicholson, W., Rosoff, K., Strahsmeier, K., Wheeler, M., Polejaeva, I., Ayares, D., (2003). Behavioral comparisons of cloned and non-cloned pigs. Journal of Animal and Veterinary Advances, 2:8, 430-436.
- Phelps, C., Koike, C., Vaught, T., Boone, J., Wells, K., Chen, S., Ball, S., Specht, S., Monahan, J., Jobst, P., Sharma, S., Lamborn, A., Polejaeva, I., Moore, M., Demetris, A., Rudert, W., Bottino, R., Bertera, S., Trucco, M., Starzl, T., Dai, Y., Ayares, D., (2003). Production of a1,3-galactosyltransferase deficient pigs. Science, 299, 411-414.
- Chen, S., Vaught, T., Monahan, J., Boone, J., Emslie, E., Jobst, P., Lamborn, A., Schnieke, A., Robertson, L., Colman, A., Dai, Y., Polejaeva, I., Ayares, D., (2002). Efficient production of transgenic cloned calves using preimplantation screening. Biology of Reproduction, 67, 1488-1472.
- Dai, Y., Vaught, T., Boone, J., Chen, S., Phelps, C., Ball, S., Monahan, J., Jobst, J., McCreath, K., Lamborn, A., Cowell-Lucero, J., Wells, K., Colman, A., Polejaeva, I., Ayares, D., (2002). Targeted disruption of the α1, 3-galactosyltransferase gene in cloned pigs. Nature biotechnology, 20, 251-255.
- Polejaeva, I., (2001). Pig cloning: advances and applications. Reproduction, 58, 293-300.
- Polejaeva, I., Chen, S., Vaught, T., Page, R., Mullins, J., Dai, Y., Boone, J., Walker, S., Ayares, D., Colman, A., Campbell, K., (2000). Cloned Piglets Produced by Nuclear Transfer from Adult Somatic Cells. Nature, 407, 86-90.
- Polejaeva, I., Campbell, K., (2000). New advances in somatic cell nuclear transfer: application in transgenesis. Theriogenology, 53, 117-126.
- Polejaeva, I., Reed, W., Bunch, T., Ellis, L., White, K., (1997). Effect of Prolactin on the Reactivation of Mink blastocysts in Obligate Diapause in Vitro and Embryonic Stem Cells Establishment. Journal of Reproduction & Fertility, 109, 229-236.
- Wolf, E., Kramer, R., Polejaeva, I., Thoenen, H., Brem, G., (1994). Efficient generation of chimaeric mice using embryonic stem cells after long-term culture in the presence of ciliary neurotrophic factor. Transgenic Research, 3, 152-158.
- Rutigliano, H., Wilhelm, A., Hall, J., Shi, B., Meng, Q., Stott, R., Bunch, T.D, White, K.L, Davies, C., Polejaeva, I., Cytokine gene expression at the maternal?fetal interface after somatic cell nuclear transfer pregnancies in small ruminants.. Reproduction, Fertility and Development
Professional Journal
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Publications | Other
Newsletter
- Polejaeva, I., Gregg, K., Kraemer, D., (2011). Biosafety issues and mitigations regarding the use of tissues and oocytes for cloning. Embryo Transfer Newsletter
Other
- Polejaeva, I., Wang, Z., Hu, S., Ranjan, R., Davies, C., Thomas, A., White, K.L, (2015). Method for transgenic bovidae expressing cardiac fibrosis and associated pathology. United States Patent Application Publication *
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.