Zhongde Wang

Animal, Dairy and Veterinary Sciences (ADVS)

Professor


Zhongde Wang

Contact Information

Office Location: Bioinnovations Building 305K
Phone: 435-797-9668
Email: zonda.wang@usu.edu

Educational Background

Nuclear reprogramming by somatic cell nuclear transfer, (Embryonic stem cells and genetic engineering), Massachusetts Institute of Technology, 2004
PhD, Molecular and Cellular Biology, University of Massachusetts at Amherst, 2000
Towards the isolation of esterase and amidase catalytic antibodies: Examination of germinal center diversity by cloning and sequence analysis of genes encoding monoclonal antibodies elicited by a transition state analogue

Biography

Dr. Zhongde Wang is a professor in the Department of Animal, Dairy and Veterinary Sciences at Utah State University. Dr. Wang received his Ph.D. degree in Molecular and Cellular Biology from University of Massachusetts at Amherst and did his postdoctoral training at the Whitehead Institute/Massachusetts Institute of Technology.

Teaching Interests

Metabolic syndromes, Genome engineering, Biotechnology, and Stem cells

Research Interests

Dr. Wang’s research team employs modern genome engineering tools (such as CRISPR/Cas9) and assisted reproduction technologies (such as IVF, ICSI, and somatic cell nuclear transfer or cloning) to create genetically engineered animal models for human diseases. The Wang laboratory is the first to succeed in developing genome engineering tools in the golden Syrian hamster and has produced a long list of genetic engineered hamster models, all of which are the first in the world. His laboratory is also actively pursuing a better understanding of the epigenetics of stem cells and mammalian embryo development. Current projects in Wang’s laboratory include genetic engineering in the golden Syrian hamster, guinea pig, Peromyscus, naked mole rat, and goat to create animal models of human disease. His laboratory is also actively engaged in research activities in the development of genetically engineered sheep and cattle as bioreactors for therapeutic antibody productions. The Wang laboratory is also studying embryonic stem (ES) cells and induced pluripotent stem (iPS) cells from several non-murine rodent species and farm animals. We are always looking for highly motivated, ambitious, creative, and hardworking individuals to join the lab for postdoctoral and MS/PhD trainings. If you think you have these qualities, please contact Dr. Wang directly at zonda.wang@usu.edu

Awards

CAAS Faculty Researcher of the Year, 2017

ADVS Faculty Researcher of the Year Award, 2017

Lalor Foundation Postdoctoral Fellowships , 2003

Lalor Foundation

Lalor Foundation Postdoctoral Fellowships , 2002

Lalor Foundation


Publications | Abstracts

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Publications | Journal Articles

Academic Journal

Professional Journal

  • Gilliland, T., Liu, Y., Li , R., Dunn, M., Cottle, E., Terada, Y., Ryckman, Z., Alcorn, M., Vasilatos, S., Lundy, J., Larson, D., Wu, H., Luke, T., Bausch, C., Egland, K., Sullivan, E., Wang, Z., Klimstra, W.B, (2021). Protection of human ACE2 transgenic Syrian hamsters from SARS CoV-2 variants by human polyclonal IgG from hyper-immunized transchromosomic bovines.. bioRxiv : the preprint server for biology

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Publications | Other

Other

  • Wang, Z., (2016). Correction: STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.. PLoS pathogens
  • Polejaeva, I., Wang, Z., Hu, S., Ranjan, R., Davies, C., Thomas, A., White, K.L, (2015). Method for transgenic bovidae expressing cardiac fibrosis and associated pathology. United States Patent Application Publication *

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Teaching

ADVS 6060 - Genetics of Metabolic syndromes, Fall 2021

Graduate Students Mentored

julio Landinez Aponte, Animal, Dairy & Vet Sciences
Joseph Hawkes, Animal, Dairy & Vet Sciences, September 2017
Nick Robl, Animal, Dairy & Vet Sciences, September 2016
Jinxin Miao, Other, September 2015
Dane Rasmussen, Animal, Dairy & Vet Sciences, September 2013
Jacqueline LaRose, Animal, Dairy & Vet Sciences, September 2012