Biotechnology, Epigenetics, & Stem Cell Research

Research in the Biotechnology, Epigenetics, and Stem Cell Research area is diverse and includes:

Studying embryonic stem (ES) cells and induced pluripotent stem (iPS) cells in laboratory animals (golden Syrian hamster, guinea pig, and naked mole-rat, etc.) and farm animals (cattle, goat, sheep, and pig, etc.)
Animal cloning by somatic cell nuclear transfer (SCNT) in the above-mentioned species, and studying the epigenetics of genomic reprogramming and its impacts on embryogenesis and fetal development
Developing genetically engineered non-murine animal models of human diseases
Using mice as animal models to study how nutritional and environmental exposures during prenatal development change the germline epigenome.
Mechanisms of sperm epigenetic programming and its impact on offspring health; heritable diseases of epigenetic origin (transgenic mouse models)
Establishing heterochronic gonadal somatic cell isolation and in vivo transplantation procedures in rodents
Investigations on environmental impacts on the epigenome in the context of cancer development

Associated Faculty

Professor